Introduction and objectives: Coronary artery disease is a major cause of morbidity and mortality in diabetic kidney transplant candidates. The high prevalence of coronary disease in asymptomatic patients creates the need for major coronary artery disease screening. Our goal was to determine the prevalence and prognostic factors associated with coronary disease in this patient group. Method: A retrospective study of a cohort of 36 asymptomatic patients with diabetes mellitus type 1 and 2 and chronic renal failure that were candidates for renal transplantation between January 2007 and October 2011. Results: We followed a cohort of 36 patients. Significant coronary disease was found in 65% (13) of patients with type 1 diabetes mellitus and 81.3% (13) with type 2 diabetes mellitus. In the multivariate logistic regression analysis, smoking (OR=8.3, P=.048) and glycosylated haemoglobin levels (OR=9.525, P=.006) were significantly associated with coronary artery disease. Factors not significantly associated with coronary artery disease included: age, sex, type of diabetes mellitus, duration of diabetes mellitus (years) and hypertension. Conclusion: Diabetic patients without clinical angina and chronic renal failure who were candidates for inclusion in the kidney transplant waiting list have a high prevalence of significant coronary artery disease. Smoking and glycosylated haemoglobin levels were independently associated with the presence of coronary artery disease.

Introducción y objetivos: La enfermedad arterial coronaria es una de las principales causas de morbilidad y mortalidad en pacientes diabéticos candidatos para trasplante renal. La alta prevalencia de enfermedad coronaria en pacientes asintomáticos obliga a hacer despistaje de coronariopatía significativa. Nuestro objetivo es conocer la prevalencia y los factores pronósticos asociados a enfermedad coronaria en este grupo de pacientes en nuestro medio. Métodos: Estudio observacional, descriptivo y retrospectivo de los aspectos epidemiológicos y clínicos de los pacientes diabéticos con enfermedad renal crónica candidatos a trasplante renal entre enero de 2007 y octubre de 2011. Resultados: Se analiza una cohorte de 36 pacientes. El 65% (13) con diabetes mellitus tipo 1 y el 81,3% (13) con diabetes mellitus tipo 2 presentan enfermedad coronaria significativa. En el análisis multivariado de regresión logística, se asociaron significativamente con enfermedad coronaria el tabaquismo (odds ratio [OR] = 8,3, p = 0,048) y los niveles de hemoglobina glicosilada (OR = 9,525, p = 0,006). Factores que no se asociaron significativamente a enfermedad coronaria incluyen: edad, sexo, tipo de diabetes mellitus, duración de diabetes mellitus (años) e hipertensión arterial. Conclusión: Los pacientes diabéticos sin clínica anginosa con enfermedad renal crónica candidatos a inclusión en lista de trasplante renal presentan una alta prevalencia de enfermedad arterial coronaria significativa. El tabaquismo y los niveles de hemoglobina glicosilada se asocian de forma independiente con la presencia de enfermedad arterial coronaria.

A total of 149 samples coming from Cananéia (25º lat. S) was analysed. The samples are part of Series E, Plankton Section, Oceanographic Institute of São Paulo. They were taken fortnightly from January 1958 to May 1959 at three fixed stations. Altogether 591 males, 573 females and 1426 juveniles of Lucifer faxoni Borradaile 1915 were studied. The results are as follows: 1 - There is a linear correlation between length of neck and total length. 2 - Sexual maturity is reached at 1.18 mm neck length for the males and 1.19 mm for the females. 3 - Sexual maturity peaks occur in summer and autumn. 4 - Sexual maturity stages were established according to fetasma and ovary development respectively for males and females. 5 - Based on neck length, from size groups may be traced in males. First group of smallest specimens, neck length 0.64-0.80 mm, was present in March, November 1958 and January-February 1959. The second group, neck length 0.83-1.16 mm was present all year round, except in July 1958. The third group also occurred all year round, the neck is longer than 1.18 mm. The largest males neck length 1.70-1.92 mm were present in July, September, October, November 1958 and May 1959. 6 - Females may also be classed in four categories. The first group neck length 0.54-0.90 mm was present in February, March, April, May 1958 and January, May 1959. The second group has neck length 0.95-1.16 mm. The third group has a neck length 1.19-1.79 mm. The fourth group, neck length 1.80-2.27 mm was present in June, October, November 1958 and January, May 1959; they reach larger sizes than the males. 6 - Juveniles were found throughout the year, neck length varying between 0.32-0.94 mm. 7 - The density of sexed and juveniles is slightly different. The frequency of juveniles shows two peaks, a taller one occurs from December to April and a smaller one from September to October. The frequency of sexed specimens shows only one peak that occurred from December to April. These peaks are slightly displaced as compared to the total zooplankton volume in the same area (VANNUCCI, 1962). 8 - The scarcity of specimens in January 1958 may have been caused by a fall in temperature.